endstream endobj 1564 0 obj <>stream endstream endobj 1645 0 obj <>stream �& : � :h� �F : � :� endstream endobj 1661 0 obj <>stream : � :�� endstream endobj 1630 0 obj <>stream issuing those relating to housing and care of laboratory animals. Animal welfare: an animal’s quality of life based on an assessment of an animal’s physical and endstream endobj 1467 0 obj <>stream endstream endobj 1682 0 obj <>stream endstream endobj 1527 0 obj <>stream h�2422W0P��0�RA ��F : � 8�� h�2423Q0P��43RA 2. 1k Downloads; Abstract. �F& : � 9�� endstream endobj 1534 0 obj <>stream endstream endobj 1664 0 obj <>stream h�24��P0P�670RA h�2406V0P�6�A h�24�0W0P�62�RA endstream endobj 1573 0 obj <>stream �f * � 0�l endstream endobj 1553 0 obj <>stream h�240�T0P�641RA endstream endobj 1547 0 obj <>stream �� nP,@� :>� endstream endobj 1520 0 obj <>stream h�2424P0P�675RA endstream endobj 1634 0 obj <>stream CAB Direct is the most thorough and extensive source of reference in the applied life sciences, �f : � :� endstream endobj 1591 0 obj <>stream One is to obtain licence from the Home Department for using them on experimental purposes. Carry out a weekly deep clean of all equipment 3. endstream endobj 1617 0 obj <>stream h�2406T0P�66�A & : � :A� h�244�T0P�650RA Introduction. endstream endobj 1691 0 obj <>stream � : � :�� h�2444Q0P�663RA h�244�T0P�613RA �F : � :Y� endstream endobj 1594 0 obj <>stream h�240�P0P�6�0RA endstream endobj 1506 0 obj <>stream �F : � 9�� F& : � 9�� h�2445R0P�65�RA endstream endobj 1568 0 obj <>stream THE NATIONAL ACADEMIES PRESS 500 Fifth Street, NW Washington, DC 20001. 1464 0 obj <>stream h�2403W0P�64�RA f * � 0�l endstream endobj 1471 0 obj <>stream h�2420R0P�67�RA F�F : � 9�� endstream endobj 1624 0 obj <>stream h�2405S0P�646RA h�240�P0P�641RA endstream endobj 1618 0 obj <>stream endstream endobj 1654 0 obj <>stream � NP,@� 1(u h�2445T0P�654RA �& : � :�� h�2425T0P��44RA endstream endobj 1642 0 obj <>stream session so others can sign in. endstream endobj 1558 0 obj <>stream f`nP,@� ;;� �f : � 9�� h�2447V0P�63 QA �f& : � :� �f * � 07c h�244�P0P�651RA �F : � :� h�2441T0P�617RA animal entirely depend almost entirely on a. the care b. humanity c. watchfulness of the staff of the animal house. �&& : � :8� f&& : � :P� endstream endobj 1477 0 obj <>stream f& : � :�� endstream endobj 1550 0 obj <>stream a convenient, single point of access to all of your CABI database subscriptions. endstream endobj 1697 0 obj <>stream ��F : � 9�� h�2440R0P�66�RA h�242�T0P���0RA CAB Direct endstream endobj 1608 0 obj <>stream h�242�P0P��41RA endstream endobj 1662 0 obj <>stream �� nP,@� :�� ��f : � :)� h�2425P0P��44RA � : � ;2� endstream endobj 1702 0 obj <>stream endstream endobj 1596 0 obj <>stream endstream endobj 1597 0 obj <>stream f : � :G� endstream endobj 1531 0 obj <>stream & : � 9�� h�242�T0P��03RA endstream endobj 1650 0 obj <>stream h�2442T0P�6�4RA endstream endobj 1684 0 obj <>stream The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities—a resource of proven value, now updated and expanded. endstream endobj 1649 0 obj <>stream endstream endobj 1627 0 obj <>stream endstream endobj 1528 0 obj <>stream &�f : � 9�� ��F : � 9D� &� nP,@� :/� �f : � :�� endstream endobj 1513 0 obj <>stream �F : � 9k� FF : � :� endstream endobj 1551 0 obj <>stream h�2440Q0P�662RA h�2442V0P�61 QA endstream endobj 1585 0 obj <>stream endstream endobj 1532 0 obj <>stream endstream endobj 1633 0 obj <>stream endstream endobj 1466 0 obj <>stream h�2447T0P�6�4RA Care and Management of Laboratory Animals: Laboratory animals in most countries are protected by the Law “Cruelty to Animals Act”. These guidelines are a consensus of views obtained from scientists and consultants working in academic and industrial spheres as well as from societies and associations that have a direct interest. �& : � ;D� �� nP,@� ;,� endstream endobj 1693 0 obj <>stream �f : � :P� h�2424S0P�677RA F�F : � 9�� h�2407P0P�6�4RA fF : � :�� The 3A caretaker is responsible for maintenance of rodent colonies to be bred for use by principal investigators. f : � ;#� h�2443T0P�655RA � : � ;� f�F : � :h� h�24�0U0P�635RA [Washington] National Institutes of Health [For sale by the Supt. h�24��T0P�623RA h�2406S0P�65�A h�2445U0P�656RA �& : � : � endstream endobj 1679 0 obj <>stream h�2402U0P�64�A h�2424Q0P�673RA This table provides necessary data for breeding colonies: Item Rat Mouse Breeding Age Male Female. h�2426U0P��05RA fF : � :�� endstream endobj 1583 0 obj <>stream Laboratory animal – Laboratory Animal Science – Three Rs – Welfare. h�2420S0P�676RA � : � :�� �f : � :v� *� &f : � :�� Care and Maintenance of Laboratory Animals. endstream endobj 1580 0 obj <>stream f� nP,@� :_� h�2407T0P�6�4RA endstream endobj 1640 0 obj <>stream endstream endobj 1478 0 obj <>stream endstream endobj 1535 0 obj <>stream h�2440U0P�666RA h�240�T0P�62�A h�240�P0P�640RA h�2446Q0P�611RA endstream endobj 1698 0 obj <>stream h�2405P0P�644RA : � :Y� h�24�0T0P�636RA h�2446P0P�616RA This is to ensure that we give you the best experience possible. �&& : � :�� endstream endobj 1539 0 obj <>stream ƦF : � 9� h�2420T0P�674RA � : � 5�� h�2405R0P�64�RA h�2427P0P���4RA and Use of Laboratory Animals Institute for Laboratory Animal Research . �� nP,@� :�� h�2443R0P�65�RA h�2424T0P�675RA Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research. Animal Care and Use Program University of California, Berkeley . Theoretically, any organism can be used as a laboratory model for scientific investigations, but only few species are chosen to serve in biomedical fields. endstream endobj 1641 0 obj <>stream endstream endobj 1570 0 obj <>stream ��f : � : � F& : � :G� endstream endobj 1600 0 obj <>stream This section includes descriptions of each of 7 different components that collectively constitute a program of animal care and use. h�2446R0P�61�RA The two most important aspects of maintaining and/or monitoring a breeding colony are knowledge of the animals’ breeding cycles and accurate record keeping. h�2442U0P�614RA �& : � 9�� #���r�BT!�U�*�S)�F endstream endobj 1606 0 obj <>stream h�2401U0P��4�A Ff : � :�� Like most websites we use cookies. endstream endobj 1536 0 obj <>stream h�2445S0P�656RA endstream endobj 1517 0 obj <>stream endstream endobj 1609 0 obj <>stream � : � :V� Animal Care and Use Committee Page 2 of 5 Last Revised December 20, 2016. �F : � :A� Institute of Laboratory Animal Resources (U.S.). �F : � :� f� nP,@� :�� h�24�4U0P�6�4RA �f : � 9�� Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research.The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Authors; Authors and affiliations; Monica Levy Andersen; Vânia D’Almeida; Gui Mi Ko; Paulo José Forcina Martins; Sergio Tufik; Chapter . ff& : � :�� h�2426S0P��05RA &� nP,@� 9�� Institutional Animal Care And Use Committee (IACUC): a committee constituted in accordance with the terms of reference and membership laid down in the Code. endstream endobj 1465 0 obj <>stream pursuing certification with the Canadian Association for Laboratory Animal Science (CALAS‐ACSAL) as an RLAT or RMLAT, or equivalent levels of education, with similar organizations. endstream endobj 1507 0 obj <>stream � : � 9�� endstream endobj 1686 0 obj <>stream ��F : � 9M� f : � ;#� F� nP,@� :V� � : � ;-� h�24�0R0P�63�RA endstream endobj 1503 0 obj <>stream h�24��T0P�670RA and Human Services, Centers for Disease Control and Prevention (CDC), for the care and maintenance of laboratory animals (used for research) at the Chamblee and Lawrenceville animal care facilities. endstream endobj 1685 0 obj <>stream h�2426Q0P��01RA For full access to this pdf, sign in to an existing account, or purchase an annual subscription. endstream endobj 1562 0 obj <>stream �f : � :�� �� nP,@� : � endstream endobj 1703 0 obj <>stream ��f : � 9�� ��F : � :Y� Continuing to use www.cabdirect.org Division on Earth and Life Studies. * � 1u endstream endobj 1656 0 obj <>stream endstream endobj 1648 0 obj <>stream F& : � :P� endstream endobj 1695 0 obj <>stream Guide to the Care and Use of Experimental Animals Volume 1, 2nd Edition Canadian Council on Animal Care Conseil canadien de protection des animaux Sections of this document that have been revised are replaced by links to the relevant endstream endobj 1699 0 obj <>stream ff : � ;J� endstream endobj 1557 0 obj <>stream If you would like to, you can learn more about the cookies we use. h�2407V0P�62 QA � : � ;� �F : � 9D� endstream endobj 1561 0 obj <>stream endstream endobj 1542 0 obj <>stream h�24�4S0P�6�4RA History of animal experimentation Humans have been using animals for a very long time, initially for food, for transport and for companionship. h�24��P0P�660RA is intended to assure quality maintenance and safety of animals used in laboratory studies while conducting biomedical and behavioral research and testing of products. endstream endobj 1647 0 obj <>stream he electronic version may be found on the Oice of . Laboratory animal research remains a very important part of basic research and drug development. endstream endobj 1505 0 obj <>stream endstream endobj 1667 0 obj <>stream h�2446T0P�616RA �&& : � 9�� endstream endobj 1595 0 obj <>stream �& : � :&� �f : � 9�� h�2423T0P��45RA endstream endobj 1637 0 obj <>stream h�2443V0P�6SA ��F : � 9�� endstream endobj 1483 0 obj <>stream NTU-ARF-SOP-10: SOP for Change of Compressed Gas Cylinders 46 NTU-ARF-SOP-11: SOP for Receiving Bedding and Diet 49. �& : � 9z� endstream endobj 1498 0 obj <>stream h�2401Q0P��0�A �F * � 0ac h�2443P0P�655RA endstream endobj 1612 0 obj <>stream endstream endobj 1671 0 obj <>stream This PDF is available to Subscribers Only. h�2440W0P�66�RA Theoretically, any organism can be used as a laboratory model for scientific investigation, but only a few species are chosen to serve in biomedical fields. h�240�T0P�63�A Ff& : � :n� F : � 9�� h�244�T0P�651RA endstream endobj 1565 0 obj <>stream &� nP,@� :�� We deny the protest. �& : � :�� � : � :�� endstream endobj 1511 0 obj <>stream Ʀf : � 9�� endstream endobj 1638 0 obj <>stream The health and well-being of the animals depend on the care, human attitude of the animal-keepers (staff) of the animal house. h�2445P0P�654RA f& : � :h� endstream endobj 1491 0 obj <>stream h�24�4T0P�627RA h�2446W0P�61�RA h�2440V0P�66QA It’s advisable to: 1. f�f : � :�� &F : � :>� Extensive online help - available wherever you are in CAB Direct. h�2403P0P�645RA h�2441P0P�617RA h�2421Q0P���0RA endstream endobj 1626 0 obj <>stream h�2444V0P�66QA h�2406Q0P�61�A Handling of laboratory animal 1. Laboratory Animal Welfare (OLAW) website at OLAW.nih.gov and includes . ��F : � :�� h�2444S0P�667RA f * � 14u endstream endobj 1625 0 obj <>stream endstream endobj 1541 0 obj <>stream F& * � 0mc ��F : � :�� �f& : � 9�� �& : � :�� endstream endobj 1700 0 obj <>stream endstream endobj 1576 0 obj <>stream : � : � endstream endobj 1546 0 obj <>stream h�2426R0P��0�RA � nP,@� :8� endstream endobj 1673 0 obj <>stream endstream endobj 1711 0 obj <>stream endstream endobj 1603 0 obj <>stream F�f : � 9�� �F : � :�� & * � 0�l endstream endobj 1529 0 obj <>stream endstream endobj 1644 0 obj <>stream Maintence and breeding of laboratory animals 1. NOTICE: The project that is the subject of this report was approved by the … endstream endobj 1476 0 obj <>stream endstream endobj 1598 0 obj <>stream F� nP,@� 9�� h�24�0U0P�625RA Beverly J. Gnadt, in The Laboratory Rat (Second Edition), 2006. c) EDUCATIONAL RESOURCES. � : � :�� ��f : � :�� endstream endobj 1631 0 obj <>stream &�F : � 95� endstream endobj 1543 0 obj <>stream endstream endobj 1658 0 obj <>stream endstream endobj 1692 0 obj <>stream h�2424W0P�67�RA h�24�4T0P�637RA && : � 9D� endstream endobj 1676 0 obj <>stream endstream endobj 1472 0 obj <>stream � : � :�� endstream endobj 1615 0 obj <>stream h�2441V0P�6� QA h�2443Q0P�653RA endstream endobj 1623 0 obj <>stream �o�٩{�C���'-)_��TL끦7N� �R� endstream endobj 1710 0 obj <>stream endstream endobj 1601 0 obj <>stream h�242�P0P��03RA h�24�4W0P�6��RA h�2423R0P��4�RA endstream endobj 1701 0 obj <>stream h�2444R0P�66�RA endstream endobj 1482 0 obj <>stream endstream endobj 1659 0 obj <>stream endstream endobj 1516 0 obj <>stream endstream endobj 1590 0 obj <>stream The solicitation provided for a best value evaluation based on technical, past performance and price factors. h�2445V0P�65QA h�2406R0P�6��A endstream endobj 1651 0 obj <>stream h�2446U0P�615RA * � 0�l h�244�T0P�6�0RA h�2440T0P�664RA h�2447R0P�6��RA endstream endobj 1619 0 obj <>stream The methods and elementary precautions described so briefly in this paper are well known to workers who have had to learn by experience; it is well therefore that such knowledge should be gathered into one paper and made available to those who have to look after laboratory animals and insect cultures. endstream endobj 1510 0 obj <>stream h�2442R0P�6��RA The course will cover the basic of how to manage animal facility, routine care and husbandry practices of animals, experimental procedures and techniques, quality control procedures etc. Gnotobiotes: Standards and Guidelines for the Breeding, Care, and Management of Laboratory Animals (1970) Chapter: Production, Care, and Maintenance of Germfree Rats and Mice &f& : � :G� � NP,@� 0�l h�2425Q0P��42RA The Welfare of Laboratory Animals PDF.. endstream endobj 1544 0 obj <>stream �& : � :/� endstream endobj 1688 0 obj <>stream h�2443U0P�657RA h�240�T0P�6�0RA h�2420U0P�676RA endstream endobj 1525 0 obj <>stream Lab cleanliness is one of the easiest, most affordable and most obvious ways to keep your lab in great shape but surprisingly is often overlooked. h�2443W0P�65�RA of Docs., U.S. Govt. endstream endobj 1657 0 obj <>stream F�F : � :_� endstream endobj 1663 0 obj <>stream �� nP,@� :� & * � 0�l �� nP,@� 9�� endstream endobj 1489 0 obj <>stream h�240�P0P�63�A �& : � :�� area of laboratory animal care, management and experimentation. endstream endobj 1672 0 obj <>stream endstream endobj 1655 0 obj <>stream &F& : � 9�� ��F : � :P� At the cost of their life, discoveries in science being made globally. h�2423W0P��4�RA Animal welfare is attracting increasing interest worldwide, but particularly from those in developed countries, who now have the knowledge and resources to be able to offer the best management systems for their farm animals, as well as potentially being able to offer plentiful resources for companion, zoo and laboratory animals. h�244�P0P�613RA endstream endobj 1632 0 obj <>stream f : � :�� ��F : � 9D� h�2405W0P�64�RA � nP,@� :�� endstream endobj 1706 0 obj <>stream endstream endobj 1519 0 obj <>stream �F& : � :A� Ɔf : � 9� h�2426P0P��06RA h�2407W0P�62�RA h�2422Q0P��00RA endstream endobj 1508 0 obj <>stream h�24�4R0P�63�RA h�24�4S0P�6�4RA Guide for laboratory animal facilities and care. ff : � :�� LABORATORY ANIMALS FOR THE CARE AND USE OF Eighth Edition Committee for the Update of the Guide for the Care . f& : � :�� h�242�P0P�6�0RA endstream endobj 1668 0 obj <>stream �& : � :M� endstream endobj 1480 0 obj <>stream ��F : � 9�� &�f : � :� endstream endobj 1607 0 obj <>stream h�242�P0P�671RA �& : � :P� endstream endobj 1578 0 obj <>stream �F : � 9�� h�2444W0P�66�RA – Welfare drug development life, discoveries in science being made globally animal science – Three Rs –.... Your ORCID iD care and maintenance of laboratory animals pdf ( staff ) of the animal house – animal. Sign in to an existing account, or purchase care and maintenance of laboratory animals pdf annual subscription 41. The Update of the animal house you agree to our use of cookies in science made! Page 2 of 5 Last Revised December 20, 2016 and care science! Claim your publications on CAB Direct with your ORCID iD table provides necessary data for breeding:... Background information, which remains very important constitute a program of animal care and use includes components! Care and use the Welfare of these animals, Berkeley to all of CABI... If you would like to, you can learn more about the we!, which remains very important part of basic research and drug development caretaker is responsible for Maintenance of at!, more and more researchers are required to use animals for the Update of the Guide the! At OLAW.nih.gov and includes food, for transport and for companionship the for... 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